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課程名稱 (中文) 有機化學(二)
(英文) Organic Chemistry
開課單位 化學工程學系
課程代碼 C1002
授課教師 黃俊誠
學分數 3.0 必/選修 選修 開課年級 大二
先修科目或先備能力:普通化學以及有機化學(一)
課程概述與目標:介紹有機化合物的化學命名、結構、官能基、特性、反應機構、合成與反應等相關之有機化學的基本知識,以達成具備有機化合物之合成的基本能力。
教科書 Organic Chemistry, David Klein ,Wiley.
參考教材 1. Organic Chemistry, 1st Ed., David Klein ,Wiley, 2012
2. Organic Chemistry, 7th Ed., Paula Yurkanis Bruice , Pearson, 2014
圖書館電子書 http://lb20.libraryandbook.net/FE/search_viewOpen.action?bookId=YsdsdebY1871268dY
https://www.sciencedirect.com/book/9780128024447/principles-of-organic-chemistry
課程大綱 學生學習目標 單元學習活動 學習成效評量 備註
單元主題 內容綱要
1 Alcohols and Phenols Structure and Properties of Alcohols
Preparation of Alcohols via Substitution or Addition
Preparation of Alcohols via Reduction
Preparation of Alcohols via Grignard Reagents
Protection of Alcohols
Reactions of Alcohols: Substitution and Elimination
Reactions of Alcohols: Oxidation
Synthesis Strategies
認識醇與酚化合物以及反應與製備
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    2 Alcohols and Phenols Structure and Properties of Alcohols
    Preparation of Alcohols via Substitution or Addition
    Preparation of Alcohols via Reduction
    Preparation of Alcohols via Grignard Reagents
    Protection of Alcohols
    Reactions of Alcohols: Substitution and Elimination
    Reactions of Alcohols: Oxidation
    Synthesis Strategies
    認識醇與酚化合物以及反應與製備
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    3 Ethers and Epoxides; Thiols and Sulfides Introduction to Ethers
    Preparation of Ethers
    Reactions of Ethers
    Preparation of Epoxides
    Enantioselective Epoxidation
    Ring-Opening Reactions of Epoxides
    Thiols and Sulfides
    認識有機金屬化合物
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    4 Conjugated Pi Systems and Pericyclic Reactions Classes of Dienes
    Conjugated Dienes
    Electrophilic Addition
    Thermodynamic Control vs. Kinetic Control
    An Introduction to Pericyclic Reactions
    Diels–Alder Reactions
    Electrocyclic Reactions
    共軛雙烯類與環化反應
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    5 Aromatic Compounds Introduction to Aromatic Compounds
    Reactions at the Benzylic Position
    Reduction of the Aromatic Moiety
    認識芳香環化合物
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  • 平時考
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    6 Aromatic Substitution Reactions Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation
    Activating Groups
    Deactivating Groups
    Halogens: The Exception
    Determining the Directing Effects of a Substituent
    Multiple Substituents
    Synthesis Strategies
    Nucleophilic Aromatic Substitution
    Elimination-Addition
    Identifying the Mechanism of an Aromatic Substitution Reaction
    芳香環化合物的相關反應
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    7 Aromatic Substitution Reactions Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation
    Activating Groups
    Deactivating Groups
    Halogens: The Exception
    Determining the Directing Effects of a Substituent
    Multiple Substituents
    Synthesis Strategies
    Nucleophilic Aromatic Substitution
    Elimination-Addition
    Identifying the Mechanism of an Aromatic Substitution Reaction
    芳香環化合物的相關反應
  • 實作
  • 講授
  • 平時考
  • 作業
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    8 期中考 期中考 期中考
  • 期中考
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    9 Aromatic Substitution Reactions Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation
    Activating Groups
    Deactivating Groups
    Halogens: The Exception
    Determining the Directing Effects of a Substituent
    Multiple Substituents
    Synthesis Strategies
    Nucleophilic Aromatic Substitution
    Elimination-Addition
    Identifying the Mechanism of an Aromatic Substitution Reaction
    芳香環化合物的相關反應
  • 實作
  • 講授
  • 平時考
  • 作業
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    10 Aldehydes and Ketones Introduction to Aldehydes and Ketones
    Preparing Aldehydes and Ketones
    Introduction to Nucleophilic Addition Reactions
    Mechanism Strategies
    Baeyer-Villiger Oxidation of Aldehydes and Ketones
    Synthesis Strategies
    酮類與醛類的製備以及其取代相關反應
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    11 Aldehydes and Ketones Introduction to Aldehydes and Ketones
    Preparing Aldehydes and Ketones
    Introduction to Nucleophilic Addition Reactions
    Mechanism Strategies
    Baeyer-Villiger Oxidation of Aldehydes and Ketones
    Synthesis Strategies
    酮類與醛類的製備以及其取代相關反應
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    12 Carboxylic Acids and Their Derivatives Introduction to Carboxylic Acids and their Derivatives
    Preparation of Carboxylic Acids and their Derivatives
    Reactions of Carboxylic Acids and their Derivatives
    Reactivity of Carboxylic Acid Derivatives
    Preparation and Reactions of Acid Chlorides and Acid Anhydrides
    Preparation and Reactions of Esters
    Preparation and Reactions of Amides
    Preparation and Reactions of Nitriles
    Synthesis Strategies
    認識羧酸以及與其衍生物之相關反應
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    13 Carboxylic Acids and Their Derivatives Introduction to Carboxylic Acids and their Derivatives
    Preparation of Carboxylic Acids and their Derivatives
    Reactions of Carboxylic Acids and their Derivatives
    Reactivity of Carboxylic Acid Derivatives
    Preparation and Reactions of Acid Chlorides and Acid Anhydrides
    Preparation and Reactions of Esters
    Preparation and Reactions of Amides
    Preparation and Reactions of Nitriles
    Synthesis Strategies
    認識羧酸以及與其衍生物之相關反應
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  • 平時考
  • 作業
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    14 Carboxylic Acids and Their Derivatives Introduction to Carboxylic Acids and their Derivatives
    Preparation of Carboxylic Acids and their Derivatives
    Reactions of Carboxylic Acids and their Derivatives
    Reactivity of Carboxylic Acid Derivatives
    Preparation and Reactions of Acid Chlorides and Acid Anhydrides
    Preparation and Reactions of Esters
    Preparation and Reactions of Amides
    Preparation and Reactions of Nitriles
    Synthesis Strategies
    認識羧酸以及與其衍生物之相關反應
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  • 平時考
  • 作業
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    15 Alpha Carbon Chemistry: Enols and Enolates Introduction to Alpha Carbon Chemistry: Enols and Enolates
    Alpha Halogenation of Enols and Enolates
    Aldol Reactions
    Claisen Condensations
    Alkylation of the Alpha Position
    Conjugate Addition Reactions
    Synthesis Strategies
    認識烯醇類之相關反應
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    16 Alpha Carbon Chemistry: Enols and Enolates Introduction to Alpha Carbon Chemistry: Enols and Enolates
    Alpha Halogenation of Enols and Enolates
    Aldol Reactions
    Claisen Condensations
    Alkylation of the Alpha Position
    Conjugate Addition Reactions
    Synthesis Strategies
    認識烯醇類之相關反應
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    17 Amines Introduction to Amines
    Preparation of Amines
    Synthesis Strategies
    Acylation of Amines
    The Hofmann Elimination
    Reactions of Amines with Nitrous Acid
    Reactions of Aryldiazonium Ions
    Nitrogen Heterocycles
    認識胺與衍生物之相關反應
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    18 期末考 期末考 期末考
  • 期末考
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    教學要點概述:
    教材編選: □ 自編教材 ■ 教科書作者提供
    評量方法: 期末考:30%   期中考:30%   平時考:30%   作業:10%  
    教學資源: ■ 教材電子檔 ■ 課程網站
    教學相關配合事項:須修過普通化學(一)(二)和有機化學(一)且皆通過的同學才能修課
    課程網站:網路大學
    扣考規定:http://eboard.ttu.edu.tw/ttuwebpost/showcontent-news.php?id=504