課程大綱 Syllabus |
學生學習目標 Learning Objectives |
單元學習活動 Learning Activities |
學習成效評量 Evaluation |
備註 Notes |
序 No. | 單元主題 Unit topic |
內容綱要 Content summary |
1 | Alcohols and Phenols |
Structure and Properties of Alcohols
Preparation of Alcohols via Substitution or Addition
Preparation of Alcohols via Reduction
Preparation of Alcohols via Grignard Reagents
Protection of Alcohols
Reactions of Alcohols: Substitution and Elimination
Reactions of Alcohols: Oxidation
Synthesis Strategies |
認識醇與酚化合物以及反應與製備 |
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2 | Alcohols and Phenols |
Structure and Properties of Alcohols
Preparation of Alcohols via Substitution or Addition
Preparation of Alcohols via Reduction
Preparation of Alcohols via Grignard Reagents
Protection of Alcohols
Reactions of Alcohols: Substitution and Elimination
Reactions of Alcohols: Oxidation
Synthesis Strategies |
認識醇與酚化合物以及反應與製備 |
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3 | Ethers and Epoxides; Thiols and Sulfides |
Introduction to Ethers
Preparation of Ethers
Reactions of Ethers
Preparation of Epoxides
Enantioselective Epoxidation
Ring-Opening Reactions of Epoxides
Thiols and Sulfides |
認識有機金屬化合物 |
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4 | Conjugated Pi Systems and Pericyclic Reactions |
Classes of Dienes
Conjugated Dienes
Electrophilic Addition
Thermodynamic Control vs. Kinetic Control
An Introduction to Pericyclic Reactions
Diels–Alder Reactions
Electrocyclic Reactions |
共軛雙烯類與環化反應 |
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5 | Aromatic Compounds |
Introduction to Aromatic Compounds
Reactions at the Benzylic Position
Reduction of the Aromatic Moiety |
認識芳香環化合物 |
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6 | Aromatic Substitution Reactions |
Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation
Activating Groups
Deactivating Groups
Halogens: The Exception
Determining the Directing Effects of a Substituent
Multiple Substituents
Synthesis Strategies
Nucleophilic Aromatic Substitution
Elimination-Addition
Identifying the Mechanism of an Aromatic Substitution Reaction |
芳香環化合物的相關反應 |
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7 | Aromatic Substitution Reactions |
Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation
Activating Groups
Deactivating Groups
Halogens: The Exception
Determining the Directing Effects of a Substituent
Multiple Substituents
Synthesis Strategies
Nucleophilic Aromatic Substitution
Elimination-Addition
Identifying the Mechanism of an Aromatic Substitution Reaction |
芳香環化合物的相關反應 |
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8 | 期中考 |
期中考 |
期中考 |
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9 | Aromatic Substitution Reactions |
Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation
Activating Groups
Deactivating Groups
Halogens: The Exception
Determining the Directing Effects of a Substituent
Multiple Substituents
Synthesis Strategies
Nucleophilic Aromatic Substitution
Elimination-Addition
Identifying the Mechanism of an Aromatic Substitution Reaction |
芳香環化合物的相關反應 |
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10 | Aldehydes and Ketones |
Introduction to Aldehydes and Ketones
Preparing Aldehydes and Ketones
Introduction to Nucleophilic Addition Reactions
Mechanism Strategies
Baeyer-Villiger Oxidation of Aldehydes and Ketones
Synthesis Strategies |
酮類與醛類的製備以及其取代相關反應 |
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11 | Aldehydes and Ketones |
Introduction to Aldehydes and Ketones
Preparing Aldehydes and Ketones
Introduction to Nucleophilic Addition Reactions
Mechanism Strategies
Baeyer-Villiger Oxidation of Aldehydes and Ketones
Synthesis Strategies |
酮類與醛類的製備以及其取代相關反應 |
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12 | Carboxylic Acids and Their Derivatives |
Introduction to Carboxylic Acids and their Derivatives
Preparation of Carboxylic Acids and their Derivatives
Reactions of Carboxylic Acids and their Derivatives
Reactivity of Carboxylic Acid Derivatives
Preparation and Reactions of Acid Chlorides and Acid Anhydrides
Preparation and Reactions of Esters
Preparation and Reactions of Amides
Preparation and Reactions of Nitriles
Synthesis Strategies |
認識羧酸以及與其衍生物之相關反應 |
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13 | Carboxylic Acids and Their Derivatives |
Introduction to Carboxylic Acids and their Derivatives
Preparation of Carboxylic Acids and their Derivatives
Reactions of Carboxylic Acids and their Derivatives
Reactivity of Carboxylic Acid Derivatives
Preparation and Reactions of Acid Chlorides and Acid Anhydrides
Preparation and Reactions of Esters
Preparation and Reactions of Amides
Preparation and Reactions of Nitriles
Synthesis Strategies |
認識羧酸以及與其衍生物之相關反應 |
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14 | Alpha Carbon Chemistry: Enols and Enolates |
Introduction to Alpha Carbon Chemistry: Enols and Enolates
Alpha Halogenation of Enols and Enolates
Aldol Reactions
Claisen Condensations
Alkylation of the Alpha Position
Conjugate Addition Reactions
Synthesis Strategies |
認識烯醇類之相關反應 |
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15 | Amines |
Introduction to Amines
Preparation of Amines
Synthesis Strategies
Acylation of Amines
The Hofmann Elimination
Reactions of Amines with Nitrous Acid
Reactions of Aryldiazonium Ions
Nitrogen Heterocycles |
認識胺與衍生物之相關反應 |
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16 | 期末考 |
期末考 |
期末考 |
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