課程名稱 |
(中文) 有機化學(二) (英文) Organic Chemistry |
開課單位 | 化學工程與生物科技學系 | ||
課程代碼 | C1002A | ||||
授課教師 | 黃俊誠 | ||||
學分數 | 3.0 | 必/選修 | 選修 | 開課年級 | 大二 |
先修科目或先備能力:普通化學以及有機化學(一) | |||||
課程概述與目標:介紹有機化合物的化學命名、結構、官能基、特性、反應機構、合成與反應等相關之有機化學的基本知識,以達成具備有機化合物之合成的基本能力。 | |||||
教科書 | Organic Chemistry, David Klein ,Wiley. | ||||
參考教材 | 1. Organic Chemistry, 1st Ed., David Klein ,Wiley, 2012 2. Organic Chemistry, 7th Ed., Paula Yurkanis Bruice , Pearson, 2014 |
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圖書館電子書 | http://lb20.libraryandbook.net/FE/search_viewOpen.action?bookId=YsdsdebY1871268dY https://www.sciencedirect.com/book/9780128024447/principles-of-organic-chemistry |
課程大綱 | 學生學習目標 | 單元學習活動 | 學習成效評量 | 備註 | ||
週 | 單元主題 | 內容綱要 | ||||
1 | Alcohols and Phenols | Structure and Properties of Alcohols Preparation of Alcohols via Substitution or Addition Preparation of Alcohols via Reduction Preparation of Alcohols via Grignard Reagents Protection of Alcohols Reactions of Alcohols: Substitution and Elimination Reactions of Alcohols: Oxidation Synthesis Strategies |
認識醇與酚化合物以及反應與製備 |
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2 | Alcohols and Phenols | Structure and Properties of Alcohols Preparation of Alcohols via Substitution or Addition Preparation of Alcohols via Reduction Preparation of Alcohols via Grignard Reagents Protection of Alcohols Reactions of Alcohols: Substitution and Elimination Reactions of Alcohols: Oxidation Synthesis Strategies |
認識醇與酚化合物以及反應與製備 |
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3 | Ethers and Epoxides; Thiols and Sulfides | Introduction to Ethers Preparation of Ethers Reactions of Ethers Preparation of Epoxides Enantioselective Epoxidation Ring-Opening Reactions of Epoxides Thiols and Sulfides |
認識有機金屬化合物 |
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4 | Conjugated Pi Systems and Pericyclic Reactions | Classes of Dienes Conjugated Dienes Electrophilic Addition Thermodynamic Control vs. Kinetic Control An Introduction to Pericyclic Reactions Diels–Alder Reactions Electrocyclic Reactions |
共軛雙烯類與環化反應 |
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5 | Aromatic Compounds | Introduction to Aromatic Compounds Reactions at the Benzylic Position Reduction of the Aromatic Moiety |
認識芳香環化合物 |
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6 | Aromatic Substitution Reactions | Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation Activating Groups Deactivating Groups Halogens: The Exception Determining the Directing Effects of a Substituent Multiple Substituents Synthesis Strategies Nucleophilic Aromatic Substitution Elimination-Addition Identifying the Mechanism of an Aromatic Substitution Reaction |
芳香環化合物的相關反應 |
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7 | Aromatic Substitution Reactions | Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation Activating Groups Deactivating Groups Halogens: The Exception Determining the Directing Effects of a Substituent Multiple Substituents Synthesis Strategies Nucleophilic Aromatic Substitution Elimination-Addition Identifying the Mechanism of an Aromatic Substitution Reaction |
芳香環化合物的相關反應 |
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8 | 期中考 | 期中考 | 期中考 |
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9 | Aromatic Substitution Reactions | Introduction to Electrophilic Aromatic Substitution: Halogenation, Sulfonation, Nitration, Friedel–Crafts Alkylation, Friedel–Crafts Acylation Activating Groups Deactivating Groups Halogens: The Exception Determining the Directing Effects of a Substituent Multiple Substituents Synthesis Strategies Nucleophilic Aromatic Substitution Elimination-Addition Identifying the Mechanism of an Aromatic Substitution Reaction |
芳香環化合物的相關反應 |
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10 | Aldehydes and Ketones | Introduction to Aldehydes and Ketones Preparing Aldehydes and Ketones Introduction to Nucleophilic Addition Reactions Mechanism Strategies Baeyer-Villiger Oxidation of Aldehydes and Ketones Synthesis Strategies |
酮類與醛類的製備以及其取代相關反應 |
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11 | Aldehydes and Ketones | Introduction to Aldehydes and Ketones Preparing Aldehydes and Ketones Introduction to Nucleophilic Addition Reactions Mechanism Strategies Baeyer-Villiger Oxidation of Aldehydes and Ketones Synthesis Strategies |
酮類與醛類的製備以及其取代相關反應 |
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12 | Carboxylic Acids and Their Derivatives | Introduction to Carboxylic Acids and their Derivatives Preparation of Carboxylic Acids and their Derivatives Reactions of Carboxylic Acids and their Derivatives Reactivity of Carboxylic Acid Derivatives Preparation and Reactions of Acid Chlorides and Acid Anhydrides Preparation and Reactions of Esters Preparation and Reactions of Amides Preparation and Reactions of Nitriles Synthesis Strategies |
認識羧酸以及與其衍生物之相關反應 |
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13 | Carboxylic Acids and Their Derivatives | Introduction to Carboxylic Acids and their Derivatives Preparation of Carboxylic Acids and their Derivatives Reactions of Carboxylic Acids and their Derivatives Reactivity of Carboxylic Acid Derivatives Preparation and Reactions of Acid Chlorides and Acid Anhydrides Preparation and Reactions of Esters Preparation and Reactions of Amides Preparation and Reactions of Nitriles Synthesis Strategies |
認識羧酸以及與其衍生物之相關反應 |
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14 | Carboxylic Acids and Their Derivatives | Introduction to Carboxylic Acids and their Derivatives Preparation of Carboxylic Acids and their Derivatives Reactions of Carboxylic Acids and their Derivatives Reactivity of Carboxylic Acid Derivatives Preparation and Reactions of Acid Chlorides and Acid Anhydrides Preparation and Reactions of Esters Preparation and Reactions of Amides Preparation and Reactions of Nitriles Synthesis Strategies |
認識羧酸以及與其衍生物之相關反應 |
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15 | Alpha Carbon Chemistry: Enols and Enolates | Introduction to Alpha Carbon Chemistry: Enols and Enolates Alpha Halogenation of Enols and Enolates Aldol Reactions Claisen Condensations Alkylation of the Alpha Position Conjugate Addition Reactions Synthesis Strategies |
認識烯醇類之相關反應 |
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16 | Alpha Carbon Chemistry: Enols and Enolates | Introduction to Alpha Carbon Chemistry: Enols and Enolates Alpha Halogenation of Enols and Enolates Aldol Reactions Claisen Condensations Alkylation of the Alpha Position Conjugate Addition Reactions Synthesis Strategies |
認識烯醇類之相關反應 |
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17 | Amines | Introduction to Amines Preparation of Amines Synthesis Strategies Acylation of Amines The Hofmann Elimination Reactions of Amines with Nitrous Acid Reactions of Aryldiazonium Ions Nitrogen Heterocycles |
認識胺與衍生物之相關反應 |
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18 | 期末考 | 期末考 | 期末考 |
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教學要點概述: |