教學大綱表 (112學年度 第1學期)
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課程名稱
Course Title
(中文) 生物學與材料學之間的交互作用
(英文) The Intersection Of Biology And Materials Science
開課單位
Departments
材料工程研究所
課程代碼
Course No.
X5580
授課教師
Instructor
吳錫芩
學分數
Credit
3.0 必/選修
core required/optional
選修 開課年級
Level
研究所
先修科目或先備能力(Course Pre-requisites):適合工學院大學部三年級以上(含研究所)學生,本課程屬跨域生物醫學領域 初階應用課程。
課程概述與目標(Course Overview and Goals):This course presents the basic fundamentals of materials science on a level appropriate for students. Each topic, including metals, ceramics, polymers, composite, and further advanced materials, ranges from fundamental theories and principles to in-depth medical applications. The objective is to discuss and understand how material engineering approaches can be designed, the discipline of materials science and engineering, and their interrelationship in medicine.

1. Materials for Biomedical Applications
2. Chemical Structure of Biomaterials
3. Physical Properties of Biomaterials
4. Mechanical Properties of Biomaterials
5. Biomaterial Degradation
6. Biomaterial Processing
7. Surface Properties of Biomaterials
8. Protein Interactions with Biomaterials
9. Cell Interactions with Biomaterials
10. Biomaterial Implantation and Acute Inflammation
11. Wound Healing and the Presence of Biomaterials
12. Immune Response to Biomaterials
13. Biomaterials and Thrombosis
14. Infection, Tumorigenesis, and Calcification of Biomaterials

本課程介紹材料科學的基本原理,以金屬、陶瓷、聚合物、複合材料和先進材料等在內的主題,由基礎理論和原理切入,延伸至醫學領域應用進行探討。
課程主要目的是讓非生物醫學領域背景的學生,建立以工程跨域的角度來考量與設計應用於生物醫學領域的思維,並理解及衡量之間的相互關係。
教科書(Textbook) Biomaterials: the intersection of biology and materials science
Pearson Prentice Hall bioengineering, J. S. Temenoff, Antonios G. Mikos, Pearson Prentice Hall, 2008 (ISBN 0132350440, 9780132350440)
參考教材(Reference) Biomaterials: An Introduction, Joon Park,R.S. Lakes, Springer-Verlag
課程大綱 Syllabus 學生學習目標
Learning Objectives
單元學習活動
Learning Activities
學習成效評量
Evaluation
備註
Notes

No.
單元主題
Unit topic
內容綱要
Content summary
1 The history and scope of biomaterials 課程內容介紹 The history and scope of biomaterials
課程內容介紹
The history and scope of biomaterials
課程內容介紹
討論
講授
 
2 Introduction: Biomaterials 簡介:生醫材料 Applications of Materials in the Biomedical Field (Metals, Ceramics, Polymers, Composites
材料在生物醫學領域的應用(金屬、陶瓷、高分子、複合材)
Applications of Materials in the Biomedical Field (Metals, Ceramics, Polymers, Composites
材料在生物醫學領域的應用(金屬、陶瓷、高分子、複合材)
討論
講授
個別或小組指導
個案研究
其他評量-課堂表現
 
3 Material Analysis Techniques(I) 材料分析技術(I) Biomaterial Analysis: Metal, Ceramic
生醫材料分析:金屬、陶瓷
Understanding the Principles and Applications of Various Material Analysis Techniques in Biomedical Research and Development
了解各種生醫材料分析技術之原理及其應用
講授
個案研究
閱讀討論
報告
其他評量-課堂表現
 
4 Material Analysis Techniques(II) 材料分析技術(II) Biomaterial Analysis: Polymer, Composite
生醫材料分析:高分子、複合材料
Understanding the Principles and Applications of Various Material Analysis Techniques in Biomedical Research and Development
了解各種生醫材料分析技術之原理及其應用
講授
個案研究
閱讀討論
報告
平時考
其他評量-課堂表現
 
5 Literature Review, Case Study (I) 文獻導讀、案例討論 Realistic Scenario in Biomedical Research and Development(Exploring Needs, Interpreting Demands)
生醫材料研發真實性問題情景設定(探索需求、詮釋需求)
Establishing the Correlation between Various Biomaterial Structures, Properties, and Applications
建立各種生醫材料結構、特性、應用之間的關聯性
講授
個案研究
閱讀討論
其他評量-課堂表現
 
6 Literature Review, Case Study (II) 文獻導讀、案例討論 Realistic Scenario in Biomedical Research and Development (Exploring Needs, Interpreting Demands)
生醫材料研發真實性問題情景設定(探索需求、詮釋需求)
Establishing the Correlation between Various Biomaterial Structures, Properties, and Applications
建立各種生醫材料結構、特性、應用之間的關聯性
講授
個案研究
閱讀討論
報告
其他評量-課堂表現
 
7 Case Study: Industrial Research and Development (I) 生醫材料產業研發實例(I) NSTC program: From IP to IPO (FITI)
Case Study (Clinical): Development Journey of Innovative Medical Devices
國科會『創新創業激勵計畫(簡稱〝FITI計畫〞)』
案例討論(臨床):新創醫材發展歷程
Problem Solving, Development, and Implementation of Innovative Medical Devices
新創醫材問題對策、發展、實行
講授
協同教學
個案研究
作業
其他評量-課堂表現
 
8 Midterm Project Discussion 期中:專題討論 General Discussion on Theme Ideation
進行主題發想的總討論
Evaluation of Biomaterial Analysis Techniques
Project Discussion
材料分析技術檢核
期中專題討論
討論
個別或小組指導
閱讀討論
作業
平時考
 
9 Project Design Ideation, Exploration, and Discussion (I) 專案設計發想與探討(I) Project Design and Exploration (Defining Problems, User's Needs - Inducing Known & Unknown Information, Formulating Requirements, Identifying Key Challenges)
專案設計發想與探討(定義問題、使用者需求-歸納已知&未知訊息、擬定需求、挑戰重點)
Project Design and Exploration (Defining Problems, User's Needs - Inducing Known & Unknown Information, Formulating Requirements, Identifying Key Challenges)
專案設計發想與探討(定義問題、使用者需求-歸納已知&未知訊息、擬定需求、挑戰重點)
討論
設計研究
心得發表
個別或小組指導
閱讀討論
作業
報告
其他評量-課堂表現
 
10 Project Design Ideation, Exploration, and Discussion (II) 專案設計發想與探討(II) Student's project design/ proposal presentation、Selected articles reading
專題研究、心得發表、閱讀討論
Student's project design/ proposal presentation、Selected articles reading
專題研究、心得發表、閱讀討論
討論
設計研究
個別或小組指導
閱讀討論
作業
報告
其他評量-課堂表現
 
11 Project Design Ideation, Exploration, and Discussion (III) 專案設計發想與探討(III) Student's project design/ proposal presentation、Selected articles reading
專題研究、心得發表、閱讀討論
Student's project design/ proposal presentation、Selected articles reading
專題研究、心得發表、閱讀討論
討論
設計研究
個別或小組指導
閱讀討論
作業
報告
其他評量-課堂表現
 
12 Project Design Ideation, Exploration, and Discussion (IV) 專案設計發想與探討(IV) Student's project design/ proposal presentation、Selected articles reading
專題研究、心得發表、閱讀討論
Student's project design/ proposal presentation、Selected articles reading
專題研究、心得發表、閱讀討論
討論
設計研究
個別或小組指導
閱讀討論
作業
報告
其他評量-課堂表現
 
13 Project Design Ideation, Exploration, and Discussion (V) 專案設計發想與探討(V) Evaluating Prototype Simulation/Implementation
檢核原型模擬/實作
The application of SWOT and STP in the project proposal. Approaches to product segmentation and differentiation in research and development, understanding research dynamics, market evaluation, and strategy analysis. (Course ideation, prototype experimentation).
SWOT、STP在計畫書之應用。產品區隔與差異化研發的作法,瞭解研發動態/市場評估與策略分析。(課程發想、原型實驗)
討論
設計研究
協同教學
個別或小組指導
作業
其他評量-課堂表現
 
14 Case Study: Industrial Research and Development (II) 生醫材料產業研發實例(II) Biodesign and SPARK project experience sharing
Case Study (Clinical): Development Journey of Innovative Medical Devices
Biodesign、SPARK計畫經驗分享
案例討論(臨床):新創醫材發展歷程
Problem Solving, Development, and Implementation of Innovative Medical Devices
新創醫材問題對策、發展、實行
講授
協同教學
個案研究
作業
其他評量-課堂表現
 
15 Case Study: Industrial Research and Development (III) 生醫材料產業研發實例(III) Biomedical Commercialization Center (Prototype Project Results), Biomedical Regulations, and Patents
Case Study (Clinical): Development Journey of Innovative Medical Devices
生醫商品化中心(雛形計畫成果)、生醫法規和專利
案例討論(臨床):新創醫材發展歷程
Problem Solving, Development, and Implementation of Innovative Medical Devices
新創醫材問題對策、發展、實行
講授
協同教學
個案研究
作業
其他評量-課堂表現
 
16 Project Design Proposal 專案設計方案發表 Project Design and Exploration (Defining Problems, User's Needs - Inducing Known & Unknown Information, Formulating Requirements, Identifying Key Challenges)
專案設計發想與探討(定義問題、使用者需求-歸納已知&未知訊息、擬定需求、挑戰重點)
Project Design and Exploration (Defining Problems, User's Needs - Inducing Known & Unknown Information, Formulating Requirements, Identifying Key Challenges)
專案設計發想與探討(定義問題、使用者需求-歸納已知&未知訊息、擬定需求、挑戰重點)
討論
心得發表
個別或小組指導
作業
報告
 
17 Project Design Presentation 期末專題報告 Project Validation/Implementation Evaluation
檢核專案驗證/實作
Cultivating students' oral and written communication skills, enhancing problem-solving abilities, and fostering critical thinking skills
培養同學口語及書面溝通能力,增進解決問題能力及批判思考能力。
討論
心得發表
協同教學
個別或小組指導
報告
其他評量-課堂表現
彈性教學
 
18 Evaluation, Reflection, Review/Feedback 期末評估、反思、回顧/回饋 Evaluation, Reflection, Review/Feedback 期末評估、反思、回顧/回饋 Evaluation, Reflection, Review/Feedback 期末評估、反思、回顧/回饋 討論
心得發表
其他評量-課堂表現
彈性教學
 
彈性教學週活動規劃

No.
實施期間
Period
實施方式
Content
教學說明
Teaching instructions
彈性教學評量方式
Evaluation
備註
Notes
1 起:2024-01-01 迄:2024-01-07 5.小專題 Project Project Validation/Implementation Evaluation 檢核專案驗證/實作 Developing students’ oral and written communication skills, enhancing problem-solving abilities, and fostering critical thinking skills. 培養同學口語及書面溝通能力,增進解決問題能力及批判思考能力。
2 起:2024-01-08 迄:2024-01-14 2.非同步線上課程 Asynchronous online course Evaluation, Reflection, Review/Feedback 期末評估、反思、回顧/回饋 Evaluation, Reflection, Review/Feedback 期末評估、反思、回顧/回饋


教學要點概述:
1.自編教材 Handout by Instructor:
■ 1-1.簡報 Slids
■ 1-2.影音教材 Videos
□ 1-3.教具 Teaching Aids
□ 1-4.教科書 Textbook
□ 1-5.其他 Other
□ 2.自編評量工具/量表 Educational Assessment
□ 3.教科書作者提供 Textbook

成績考核 Performance Evaluation: 其他評量:30%   報告:20%   彈性教學:10%   平時考:20%   作業:20%  

教學資源(Teaching Resources):
□ 教材電子檔(Soft Copy of the Handout or the Textbook)
■ 課程網站(Website)
課程網站(Website):Tronclass
扣考規定:https://curri.ttu.edu.tw/p/412-1033-1254.php